Injectable bone substitute using a hydrophilic polymer
نویسندگان
چکیده
منابع مشابه
Injectable bone substitute using a hydrophilic polymer.
We studied a new injectable biomaterial for bone and dental surgery consisting of a hydrophilic polymer as matrix and bioactive calcium phosphate (CaP) ceramics as fillers. This material is composed of complex fluids whose flow is determined by the laws of rheology. We investigated the macromolecular effects on this composite in a tube. The stability of the polymer and the mixture is essential ...
متن کاملPolymer-calcium phosphate composites for use as an injectable bone substitute
Calcium phosphate (CP) materials have been used extensively for bone replacement and augmentation due to their similarity to the mineral component of bone. In addition to being non-toxic, they are biocompatible, not recognized as foreign in the body, and most importantly, exhibit bioactive behavior, being integrated into the tissue by the same processes active in remodeling healthy bone. This l...
متن کاملPolymer-calcium phosphate composites for use as an injectable bone substitute
Medical procedures to address bone related injury are prevalent in the United States, with around 900,000 hospitalizations due to fractures and over 800,000 grafting procedures annually. Calcium phosphates (CPs) are particularly promising as bone substitute materials, due to their similarity to hydroxyapatite, the mineral component of bone. In addition to being non-toxic, they are biocompatible...
متن کاملBone augmentation using a new injectable bone graft substitute by combining calcium phosphate and bisphosphonate as composite—an animal model
OBJECTIVE The aim of this study was to create a new injectable bone graft substitute by combining the features of calcium phosphate and bisphosphonate as a composite bone graft to support bone healing and to evaluate the effect of alendronate to the bone healing process in an animal model. MATERIAL AND METHOD In this study, 24 New Zealand white rabbits were randomly divided into two groups: a...
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In this study, an injectable bone substitute (IBS) consisting of citric acid, chitosan solution as the liquid phase and tetra calcium phosphate (TTCP), dicalcium phosphate anhydrous (DCPA) and calcium sulfate hemihydrate (CSH) powders as the solid phase was prepared. Four groups containing different percentages (0-30%) of calcium sulfate hemihydrate (CSH, CaSO(4) . 0.5H(2)O) were investigated. ...
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ژورنال
عنوان ژورنال: Bone
سال: 1999
ISSN: 8756-3282
DOI: 10.1016/s8756-3282(99)00146-5